Smed Advisory

Cases

17 assignments from twenty years in global pharma and medtech and from my advisory work since 2026. Company and product names are left out.

Pharma · Medtech · Transformation, digital and AI · Startups and scale-ups

Pharma

Global launch of three products

Built the launch framework. Prepared and followed up 20 to 30 affiliates, and challenged the brand plans in every major market: the US, China, Japan, EU5, Canada, Brazil and Latin America.

Result.Share taken from the market leader. The framework is still in use.

A new business area in prevention

Strategy and commercial rationale for an area next to an existing treatment business. Agreement closed across six SVP areas.

Result.The unit was set up with a budget above DKK 100M a year.

Early commercial assessment of the pipeline

eNPV and sensitivity analyses across the development portfolio. Target product profiles, conjoint studies and the assessment of two new therapy areas. Chaired an early commercial team.

Result.Commercial input to pipeline reviews at EVP level.

Investment committee in a global commercial organisation

Ran the committee for a multi-billion DKK portfolio of marketed products, devices and production capacity. Prepared the cases and settled the trade-offs. Ran the annual strategy event for more than 300 executives.

Result.Funding allocated to the most important priorities, in line with corporate strategy, so the organisation could execute on them.

Medtech

Growing a USD 200M global device business

Portfolio strategy, two new products launched and a discontinuation strategy carried out to slim the portfolio.

Result.20% growth in a market growing 10%.

A portfolio of software as a medical device

A new business area built from five to 200 people in six countries. A ten-year business plan approved by executive management. The quality management system and cloud platform built to carry the products.

Result.Products CE marked in class I and IIa and FDA cleared. In daily use by 100,000 patients in 2022.

Partnerships with medtech companies and startups

Negotiated co-development and IP terms. Structured a minority investment with board seats and right of first refusal. Took an acquisition case to executive management.

Result.Royalties tied to measurable patient outcomes, and joint steering committees with leading medtech companies.

Clinical evidence for digital solutions

Led and prioritised a real world evidence study with more than 2,500 patients. Secured a phase 3 trial combining a drug with dosing software.

Result.Six peer-reviewed publications based on the data.

Transformation, digital and AI

Reorganising a research organisation of 800

Designed the operating model after two units merged. Agreed roles and responsibilities, and rewrote the milestone deliverables in the corporate project framework.

Result.The new organisation was implemented with best in class employee satisfaction.

AI in use in a research organisation of 800

Implemented two scientific search platforms. Chat-based use cases for data cleaning and data identification. A model for which data may be used with which models, and EU AI Act classification.

Result.More than 65% of the area uses the platforms in their daily work. AI training completed.

Data governance across the research value chain

More than 40 ambassadors, one in each team. Common data definitions, and data ownership and stewardship roles put into the line.

Result.More than 30 local initiatives completed. That is what made the AI use cases work.

Prioritising a digital investment portfolio

Built a four-category model and applied it to an annual pool of DKK 200 to 250M.

Result.Around 30% of the spend taken out, and speed to milestone doubled.

Commercial workflows moved to a shared service centre

Rewrote SOPs and workflows before handover. Made the first hires in India. Moved whole workflows, never parts of them.

Result.The centre ran without the people who built it, and kept growing.

Two global commercial reorganisations

Redesigned roles and responsibilities across the global commercial organisation, directing top tier consulting teams along the way.

Result.Implemented globally.

Startups and scale-ups

Commercial build of an AI company in healthcare

Built the commercial model, pricing and subscription structure. A reactivation programme for inactive customers. Agent-based workflows behind the AI product.

Result.More than 30% growth in the customer base, and a new medical specialty opened as a second vertical.

Market access for regulated software

Market entry under MDR. Integration talks with electronic health record vendors.

Result.Live with paying clinics.

A startup partner programme at a large pharma company

Built an open developer platform around a patient data stream. A tiered partner model based on compliance, GDPR and regulatory requirements. Test tooling and joint technical steering committees.

Result.More than 30 startups integrated.